Leukemia and the nervous system.

نویسنده

  • Marc C Chamberlain
چکیده

Leukemia affects the central and peripheral nervous system. Neurologic complications are a consequence of direct leukemic infiltration, as occurs with leukemic meningitis, and due to complications of either antileukemic treatment (thrombocytopenic or disseminated intravascular coagulation-related intracranial hemorrhage, steroid myopathy, vinca alkaloid peripheral neuropathy) or immune compromise (Herpes zoster shingles or Aspergillus meningitis).

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Central nervous system relapse prophylaxis in acute lymphoblastic leukemia (ALL) intrathecal chemotherapy with and without cranial irradiation

Background: Central Nervous System (CNS) relapse in acute lymphoblastic leukemia was significantly decreased due to the use of new chemotherapyeutic agents, Intrathecal chemotherapy and cranial irradiation. The purpose of this study was to compare the effectiveness of intrathecal (IT) CNS chemotherapy alone versus combination of IT chemotherapy with cranial irradiation for prevention of CNS rel...

متن کامل

The role of supine and prone positions on central nervous system involvement in patients with acute lymphoblastic leukemia

Background: Acute lymphoblastic leukemia (ALL) affects both children and adults, with a peak incidence between the ages of 2 and 5 years. ALL cells sometimes penetrate the central nervous system (CNS) and patients with CNS diseases at initial presentation have been reported to experience a significantly greater risk of treatment failure compared with CNS negative patients. This study hypothesiz...

متن کامل

The Effects of Prophylactic Treatment of the Central Nervous System on the Intellectual Functioning Of Children with Acute Lymphocytic Leukemia

Abstract Objective The great majority of patients with childhood leukemia become long-term survivors. They treated with chemotherapy and prophylactic central nervous system (CNS) irradiation. The aim of this cross-sectional study was to evaluate effect of the long-term toxicity in ALL survivors, and possible effects of this treatment on their intellectual in compare with their sibling. Mater...

متن کامل

Brain MRI Findings in Children with Acute Lymphoblastic Leukemia

Background: Patients with leukemia are facing more complications in order to achieve longer survival. We aimed to evaluate the frequency of central nervous system abnormalities (CNS) on MRI of children with acute lymphoblastic leukemia (ALL). Methods: Sixty-six children with diagnosis of ALL aged 2-18 years were recruited. Non-contrast sequences of brain MRI in addition to diffusion weighted i...

متن کامل

Application of Artificial Neural Networks in a Two-step Classification for Acute Lymphocytic Leukemia Diagnosis by Blood Lamella Images

Introduction: This study aimed to present a system based on intelligent models that can enhance the accuracy of diagnostic systems for acute leukemia. The three parts including preprocessing, feature extraction, and classification network are considered as associated series of actions. Therefore, any dysfunction or poor accuracy in each part might lead in general dysfunction of...

متن کامل

The relation between end of induction minimal residual disease and different risk factors in patients with acute lymphoblastic leukemia

Background: Malignant disorder with B or T stem cell basis leads to development and continuation of acute lymphoblastic leukemia (ALL) due to aggregation of blast cells in bone marrow. The environmental, genetic, and demographic factors may influence the disease relapse. The objective of this study was to assess the relation between end of induction minimal residual disease and different risk f...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Current oncology reports

دوره 7 1  شماره 

صفحات  -

تاریخ انتشار 2005